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Publications

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Publications

• 2013

  • Shin J, Lee JC, Baek KH, 2013: A single extra copy of Dscr1 improves survival of mice developing spontaneous lung tumors through suppression of tumor angiogenesis.. Cancer Letters, doi:pii: S0304-3835(13)00665-4  

  • Yong Kim S, Jeong S, Chah KH, Jung E, Baek KH, Kim ST, Shim JH, Chun E, Lee KY., 2013: Salt-Inducible Kinases 1 and 3 Negatively Regulate Toll-Like Receptor 4-Mediated Signal.. Mol Endocrinol., 2013 Sep 23. [Epub ahead of pr  

  • Baek KH, Bhang D, Zaslavsky A, Wang LC, Vachani A, Kim CF, Albelda SM, Evan GI, Ryeom S., 2013: Thrombospondin-1 mediates oncogenic Ras-induced senescence in pre-malignant lung tumors. J. Clin. Invest., doi:pii: 67465. 10.1172/JCI674  

  • Lee JC, Shin J, Baek KH, 2013: Trisomy of the Dscr1 gene suppresses early progression of pancreatic intraepithelial neoplasia driven by oncogenic Kras.. Biochem Biophys Res Commun, doi:pii: S0006-291X(13)01504-0  

  • Ki CS, Jung CL, Kin HJ, Baek KH, Park SJ, On YK, Kim KS, Noh SJ, Youm JB, Kim JS, Cho H., 2013: A KCNQ1 mutation causes age-dependant bradycardia and persistent atrial fibrillation.. Pf lügers Archiv - European Journal of Phy siology, [Epub ahead of print]  

  • Shin J, Yang J, Lee JC, Baek KH., 2013: Depletion of ERK2 but not ERK1 abrogates oncogenic Ras-induced senescence.. Cellular Signalling, 25(12), 2540-2547  

  • Zaslavsky A, Chou ST, Schadler K, Lieberman A, Pimkin M, Kim YJ, Baek KH, Aird WC, Weiss MJ, Ryeom S., 2013: The calcineurin-NFAT pathway negatively regulates megakaryopoiesis.. Blood, 121(16), 3205-3215.  

 

• 2010

  • Zaslavsky A, Baek KH, Lynch RC, Short S, Grillo J, Folkman J, Italiano JE, and Ryeom S, 2010: Platelet-derived thrombospondin-1 (TSP-1) is a critical negative regulator and potential biomarker of angiogenesis.. Blood. 115. 4605-4613., 115(22), 4605-4613  

  • Zaslavsky A, Chen C, Grillo J, Baek KH, Holmgren L, Yoon S, Folkman J, and Ryeom S, 2010: Regional Control of Tumor Growth.. Mol. Cancer Res. 2010 Aug 24. [Epub ahead of print], 8(9), 1198-1206  

  • Kim HS, Baek KH, Ha GH, Lee JC, Kim YN, Lee J, Park HY, Lee NR, Lee H, Cho Y, Lee CW, 2010: The hsSsu72 phosphatase is a cohesion-binding protein that regulates the resolution of sister chromatid arm cohesion.. EMBO J. 2010 Sep 3. [Epub ahead of print], 29(20), 3544-3557  

 

• 2009

  • Ryeom S, Baek KH, and Zaslavsky A, 2009: Down's syndrome: protection against cancer and the therapeutic potential of DSCR1.. Future Oncol. 5.1185-1188.  

  • Baek KH*, Zaslavsky A*, Lynch R*, Britt C, Okada Y, Siarey R, Lensch W, Park IH, Yoon S, Minami T, Reeves R, Korenberg J, Folkman J, Daley G, Aird W, Galdzicki Z, and Ryeom S, 2009: Down’s syndrome suppression of tumor growth and the role of the calcineurin inhibitor DSCR1.. Nature. 459. 1126-1130.  

  • Yoon SS, Stangenberg L, Lee YJ, Rothrock C, Dreyfuss JM, Baek KH, Waterman PR, Nielsen GP, Weissleder R, Mahmood U, Park PJ, Jacks T, Dodd RD, Fisher CJ, Ryeom S, Kirsch DG, 2009: Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma.. Int. J. Radiat. Oncol. Biol. Phys. 74. 1207-1216.  

 

• 2008

  • Foo S, Ma Y, Ruas J, Bommi-Reddy A, Girnun J, Cooper M, Laznik D, Rosenzweig A, Spiegelman B, Chinsomboon J, Baek KH, and Arany Z, 2008: HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1.. Nature. 451, 1008-1012.  

  • Ryeom S, Baek KH, Rioth M, Lynch R, Zaslavsky A, Birsner A, Yoon S, and McKeon F, 2008: Targeted Deletion of the Calcineurin Inhibitor DSCR1 Suppresses Tumor Growth.. Cancer Cell. 13, 420-431.  

 

 

• 2007

  • Ha GH, Baek KH, Kim HS, Jeong SJ, McKeon F, and Lee CW., 2007: p53 activation in response to mitotic spindle damage requires signaling via BubR1-mediated phosphorylation.. Cancer Res. 67, 7155-7154.  

 

• 2006

  • Baek KH, Park HY, Kang CM, Kim SJ, Jeong SJ, Hong EK, Park JW, Sung YC, Suzuki T, Kim CM, and Lee CW., 2006: Overexpression of hepatitis C virus NS5A protein induces chromosome instability via mitotic cell cycle dysregulation.. J Mol. Biol. 359, 22-34.  

 

• 2005

  • Baek KH*, Shin HJ*, Jeong SJ, Park JW, McKeon F, Lee CW, Kim CM., 2005: Caspases-dependent cleavage of mitotic checkpoint proteins in response to microtubule inhibitor.. Oncol Res. 15,161-168.  

 

• 2004

  • Ha SJ, Kim DJ, Baek KH, Yun YD, and Sung YC., 2004: IL-23 induces stronger sustained CTL and Th1 immune responses than IL-12 in hepatitis C virus envelope protein 2 DNA immunization.. J Immunol. 172, 525-531.  

  • Jeong SJ, Shin HJ, Kim SJ, Ha GH, Cho BI, Baek KH, Kim CM, and Lee CW., 2004: Transcriptional abnormality of the hsMAD2 mitotic checkpoint gene is a potential link to hepatocellular carcinogenesis.. Cancer Res. 64, 8666-8673.  

  • Yoon YM, Baek KH, Jeong SJ, Shin HJ, Ha GH, Jeon AH, Hwang SG, Chun JS, and Lee CW., 2004: WD repeat-containing mitotic checkpoint proteins act as transcriptional repressors during interphase.. FEBS Lett. 575, 23-29.  

 

• 2003

  • Baek KH*, Shin HJ*, Jeon AH, Park MT, Lee SJ, Kang CM, Lee HS, Yoo SH, Chung DH, Sung YC, McKeon F, and Lee CW., 2003: Dual roles of human BubR1, a mitotic checkpoint kinase, in the monitoring of chromosomal instability.. Cancer Cell. 4, 483-497.  

  • Kim BM, Lee DS, Choi JH, Kim CY, Son M, Suh YS, Baek KH, Park KS, Sung YC, and Kim WB., 2003: In vivo kinetics and biodistribution of a HIV-1 DNA vaccine after administration in mice.. Arch Pharm Res. 26, 493-498.  

  • Shin HJ, Baek KH, Jeon AH, Kim SJ, Jang KL, Sung YC, Kim CM, and Lee CW., 2003: Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation.. Oncogene. 22, 3853-3858.  

  • Baek KH, Shin HJ, Yoo JK, Cho JH, Choi YH, Sung YC, McKeon F, and Lee CW., 2003: p53 deficiency and defective mitotic checkpoint in proliferating T lymphocytes increase chromosomal instability through aberrant exit from mitotic arrest.. J Leukoc Biol. 73, 850-861.  

 

• 2001

  • Baek KH, Ha SJ, and Sung YC., 2001: A novel function of phosphorothioate oligodeoxynucleotides as chemoattractants for primary macrophages.. J Immunol. 167, 2847-2854.  

 

• 2000

  • Lee SW, Song MK, Baek KH, Park Y, Kim JK, Lee CH, Cheong HK, Cheong C, and Sung YC., 2000: Effects of a hexameric deoxyriboguanosine run conjugation into CpG oligodeoxynucleotides on their immunostimulatory potentials.. J Immunol. 165, 3631-3639.  

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